Effect of ulinastatin and psychological intervention on prevention of pancreatitis after endoscopic retrograde cholangiopancreatography
Objective To study and analyze the effect of ulinastatin and psychological intervention on prevention of pancreatitis after endoscopic retrograde cholangiopancreatography(ERCP). Methods 50 patients with biliary tract diseases who underwent ERCP surgery in Center Hospital in Baoji City from January 2015 to August 2016 were selected as the research objects. They were randomly divided into control group and experimental group with 25 cases in each group. The control group was given Ulinastatin treatment, experimental group on the basis of this treated with psychological intervention, pay close attention to the patient's mental status changes, communicate actively with the patients for psychological counseling advice, eliminate negative emotions, improve the therapeutic effect. The clinical indicators such as depression score (SAS), anxiety score (SDS), occurrence of pancreatitis and the days of normal recovery of urinary amylase were compared and analyzed between the experimental group and the control group. Results Before treatment, the SAS and SDS scores of the experimental group were (45.20±4.32) and (46.98 ± 4.88), there was no significant difference compared with the control group. After treatment, the SAS and SDS scores of the experimental group were (27.20±4.12) and (30.12±3.88), which were significantly better than those of the control group, with statistical significance (P<0.05). In the experimental group, the urine amylase returned to normal days was (1.78±0.32) days, significantly less than the control group was (2.15±0.92) days, with statistical significance (P<0.05). The probability of pancreatitis in the control group was 16%, which was significantly higher than that in the experimental group (4%), and the difference was statistically significant (P<0.05). Conclusion The clinical efficacy of ulinastatin and psychological intervention in the prevention of pancreatitis after ERCP is ideal, which can significantly improve the negative emotions of patients and improve the clinical symptoms.
NETL
NSTL
万方数据
维普
