Combined detection of folic acid, vitamin B12, ferritin in anemia
Objective To evaluate the significance of combined detection of folic acid (FA), vitamin B12 and ferritin (SF) in anemia. Methods 2154 cases of patients with anemia from June 2015 to February 2017 in Huzhou First People's Hospital were as anemia group (including small cell anemia and large cell anemia group), were selected for examination in our hospital but without a diagnosis of anemia in 1000 cases as control group, were detected with folic acid and vitamin B12, ferritin levels, comparison each group of folic acid, vitamin B12 and ferritin positive rate, and record the folic acid and vitamin B12 and ferritin detection alone and combined detection results. Results Small cell anemia group and large cell anemia in patients with folic acid and vitamin B12 levels were significantly lower than the control group (P<0.05); large cell anemia patients with ferritin levels were significantly higher than that of small cell anemia group and control group (P<0.05). The positive rates of folic acid, vitamin B12 and ferritin in anemia group were significantly higher than those in control group (P<0.05), and the difference was statistically significant. The detection rate of combined detection of folic acid, vitamin B12 and ferritin in large and small cell anemia was significantly higher than that of any single detection rate, the difference was statistically significant (P<0.05). Conclusion The combined detection of folic acid, vitamin B12 and ferritin is of great significance in the diagnosis of anemia and the identification of anemia types. Decreased ferritin or reduced folate or vitamin B12 can be used in the diagnosis of small cell low pigmented anemia; folic acid and vitamin B12 reduction can be used for the diagnosis of megaloblastic anemia.
NETL
NSTL
万方数据
维普
