Application of ischemic modified albumin, CKMB and troponin I in the diagnosis of acute coronary syndrome
Objective To study the application of ischemic modified albumin, CK-MB and troponin I in the diagnosis of acute coronary syndrome. Methods 34 patients with acute coronary syndrome treated in Tianjin Ninghe district hospital from September 2015 to December 2016 and 34 healthy volunteers treated in this hospital were selected. Those patients were divided into the control group and the observation group. The control group was healthy volunteers. The observation group was patients with acute coronary syndrome. The positive, negative and specificity of CK-MB, cTnl, IMA area, CK-MB, cTnl and IMA under ROC curve and the results were measured. Results The positive rate of IMA was 23.52%, the specific rate was 76.47%, the positive rate of CK-MB was 17.64% and the specific rate was 82.35%. The positive rate of cTnl was 11.76%, the specific rate was 88.23%, the positive rate and specific rate of each index were significantly different (P<0.05). The area of IMA was significantly higher than that of CK-MB and below cTnl (P<0.05). After examination, compared with the control group, the levels of IMA, CK-MB and cTnl in the observation group were significantly different (P<0.05). Conclusion Combined detection of IMA, CK-MB and cTnl has important value in early accurate diagnosis of acute coronary syndrome, which can reduce missed diagnosis, and has a positive effect on improving the clinical efficacy.