Application of N- end brain natriuretic peptide combined with hypersensitive C reactive protein test in heart failure
Objective To investigate the significance of combined detection of N- end brain natriuretic peptide (NT-pro BNP) and hypersensitive C reactive protein (hs-CRP) in the diagnosis and treatment of heart failure. Methods 55 cases of heart failure patients from June 2014 to August 2015 were as the experimental group, another 55 cases of healthy physical examination at the same period were selected as control group. The experimental group was graded according to the American Heart Association (NYHA) heart function classification standard, 28 cases of grade II, 17 cases of grade III and 10 cases of grade IV. Serum hs-CRP and NT-proBNP levels were detected in the two groups, and the levels of NT-pro, BNP and hs-CRP in the experimental group were measured after treatment with 30D. Hs-CRP is >3 mg/L is positive, NT-proBNP is > 300 pg/L is positive, and the positive detection rate (sensitivity) is calculated separately or in combination. Results The levels of hs-CRP, NT-pro and BNP in the experimental group were higher than those in the control group, and increased with the degree of heart failure. The serum levels of hs-CRP, NT-pro and BNP in the experimental group were significantly lower than those before the treatment of 30 days. The positive rates of hs-CRP and NT-pro BNP were 90.9% and 92.7%, respectively, and the positive rate of combined detection of two and 96.3% was higher. Conclusion NT-pro BNP combined with hs-CRP has better detection effect on heart failure. It can be used as an important indicator in the diagnosis of heart failure and curative effect.
N- end of brain natriuretic peptidehypersensitivity C reaction proteinheart failure
NETL
NSTL
万方数据
维普
