Preliminary analysis of the early curative effect of Alteplase for intravenous thrombolytic therapy for acute cerebral infarction
Objective To investigate the early curative effect factors of Alteplase for intravenous thrombolysis. Methods Clinical data of 90 patients with acute cerebral infarction for Alteplase treatment was retrospectively analyzed, according the NIHSS scores, patients were divided into the thrombolysis effective group and the thrombolysis ineffective group, the differences in clinical data of the two groups were compared by single factor and multifactor regression. Results Results of univariate analysis showed that the early curative effect after thrombolysis associated with 3 months prognosis (P=0.000). Analysis showed that systolic blood pressure before thrombolysis is closely related to early curative effect after thrombolysis (P=0.009). Conclusion The prognosis of the patients for 3 months after thrombolysis is good, and the early curative effect of patients who has low systolic blood pressure before thrombolytic therapy and patients with non chronic atrial fibrillation received good outcomes after the thrombolysis.
alteplasecerebral infarctiontissue type plasminogen activatorefficacyprognosis
NETL
NSTL
万方数据
维普
