首页|Ⅲ、Ⅳ期乳腺癌及乳腺癌术后患者血清标志物检测的临床应用价值

Ⅲ、Ⅳ期乳腺癌及乳腺癌术后患者血清标志物检测的临床应用价值

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目的 探讨血清标志物检测在Ⅲ、Ⅳ期乳腺癌及乳腺癌术后患者中的应用价值.方法 选取台州市肿瘤医院2015年2月~2017年2月收治的乳腺疾病患者200例,依据病理类型分组,其中乳腺良性肿瘤组50例,乳腺癌组100例(Ⅰ~Ⅱ期60例,Ⅲ~Ⅳ期40例),术后进展复发组50例,对比血清标志物检测情况.结果 乳腺癌组、乳腺癌术后进展复发组CEA、CA15-3、CA125检测阳性率明显高于乳腺癌良性组,乳腺癌Ⅲ~Ⅳ期组各阳性率均高于Ⅰ~Ⅱ期组,联合检测阳性率均明显高于单项检测(P<0.05).结论 针对Ⅲ、Ⅳ期乳腺癌及乳腺癌术后病例,应用CEA、CA15-3、CA125联合检测效果明显优于单项检测,可为临床诊断及预后评估提供准确参考依据.
Clinical value of serum markers in patients with breast cancer and breast cancer after operation of stage III and IV
Objective To investigate the clinical value of serum markers in patients with breast cancer and breast cancer after operation of stage III and IV. Methods 200 cases of patients with breast disease were admitted to our hospital from February 2015 to February 2017, according to the pathological type of benign breast tumor group, which group of 50 cases, 100 cases of breast cancer group (60 cases of stage I and II, III - IV 40 cases), 50 cases of recurrence in postoperative contrast serum marker object detection. Results Breast cancer group, postoperative breast cancer recurrence in group CEA, CA15-3, CA125 positive rate was significantly higher than that of benign breast cancer, breast cancer stage III and IV group positive rates were higher than those of stage I and II group, the positive rate of combined detection was significantly higher than that of single detection (P<0.05). Conclusion The combined detection of CEA, CA15-3 and CA125 is superior to single detection for the cases of breast cancer and breast cancer after stage III and IV, which can provide an accurate reference for clinical diagnosis and prognosis evaluation.

stage III - IV breast cancerpostoperative progressionrecurrenceserum markersvalue

王培恩、吴仙丹

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台州市肿瘤医院 肿瘤外科,浙江 温岭 317502

温岭市第一人民医院 急危重中心,浙江 温岭 317500

Ⅲ~Ⅳ期乳腺癌 术后进展复发 血清标志物 价值

2017

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
年,卷(期):2017.37(11)
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