枸橼酸铋钾、奥美拉唑、克拉霉素、呋喃唑酮联合在消化性溃疡穿孔修补术后的应用观察
Observation of the application of bismuth potassium citrate, omeprazole, clarithromycin and furazolidone in the repair of peptic ulcer perforation
郑俊杰1
作者信息
- 1. 天津市第四中心医院 肝胆胃肠外科,天津 300140
- 折叠
摘要
目的 分析枸橼酸铋钾、奥美拉唑、克拉霉素、呋喃唑酮联合在消化性溃疡穿孔修补术后的应用观察.方法 选取天津市第四中心医院2015年7月~2017年6月收治的50例消化性溃疡穿孔修补术后患者为研究对象,随机分为2组,每组25例.实验组与对照组患者均进行消化性溃疡穿孔修补术,实验组术后进行枸橼酸铋钾、奥美拉唑、克拉霉素、呋喃唑酮联合治疗.比较分析实验组与对照组患者的临床治疗效果、复发率等临床指标.结果 治疗后,实验组治疗有效率为92.0%显著高于对照组的76.0%,差异具有统计学意义(P<0.05).术后,实验组并无复发.对照组中4例患者复发,差异具有统计学意义(P<0.05).结论 消化性溃疡穿孔修补术后应用枸橼酸铋钾、奥美拉唑、克拉霉素、呋喃唑酮联合治疗效果显著,可降低复发率,治疗有效率较高.
Abstract
Objective To analyze the application of bismuth potassium citrate, omeprazole, clarithromycin and furazolidone in the repair of peptic ulcer perforation. Methods 50 cases of peptic ulcer perforation repair from July 2015 to June 2017 were and randomly divided into two groups, 25 cases in each group. The experimental group and the control group were all treated with peptic ulcer perforation, and the experimental group was treated with bismuth potassium citrate,omeprazole, clarithromycin and furazolidone. The clinical efficacy, recurrence rate and other clinical indexes of the experimental group and the control group were compared and analyzed. Results After treatment, the effective rate of the experimental group was 92%, which was significantly higher than 76% of the control group (P<0.05). There was no recurrence in the experimental group after the operation, in the control group, 4 patients relapsed, the difference was statistically significant (P<0.05). Conclusion The effect of repair of peptic ulcer perforation after application of bismuth potassium citrate and omeprazole, clarithromycin and furazolidone combination therapy significantly, can reduce the recurrence rate, high treatment efficiency.
关键词
枸橼酸铋钾/奥美拉唑/克拉霉素/呋喃唑酮/消化性溃疡穿孔修补术Key words
bismuth potassium citrate/Omeprazole/clarithromycin/furazolidone/peptic ulcer perforation repair引用本文复制引用
出版年
2017