Intervention analysis of clinical pharmacists on antibiotic treatment course of spontaneous peritonitis in cirrhotic ascites
Objective To compare the efficacy of two different courses of antibacterial therapy on spontaneous bacterial peritonitis (SBP) in cirrhotic ascites by clinical pharmacist intervention. Methods 120 patients with spontaneous peritonitis in liver cirrhosis were divided tow groups with each 60. Anti infection treatment of two groups of patients after different treatment, the serum PCT, ascites conventional (white blood cell count, PMN count), ascites bacterial culture, blood routine, liver function, blood coagulation time (PT), C reactive protein (CRP) and other indexes, were compared before and after the intervention group comprehensive curative effect. Results There was no significant difference in the efficacy of anti infection therapy between SBP group and the control group in one week and one week after treatment. After the intervention, the antibacterial course of SBP was significantly shortened, and the use ratio of antibacterial drugs was effectively reduced. Conclusion The anti infective treatment of SBP patients is more than one week, and the effect is similar to that of one week treatment, but the meaning is not great. Through the intervention of clinical pharmacists, we can obviously prevent the abuse of antibiotics, reduce the burden and side effects of the liver, and ultimately reflect the value of intervention, and provide reference for the rational use of antibiotics in clinical practice.
NETL
NSTL
万方数据
维普
