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普通肝素剂量调整在连续性血液净化中的应用及护理

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目的 探究普通肝素剂量调整在连续性血液净化中的应用效果及护理措施.方法 选取湖州市中心医院2014年1月~2017年1月进行连续性血液净化治疗的94例患者,按照时间先后,将患者分为观察组和对照组,每组各47例,所有患者均采取连续性血液净化治疗,对照组患者肝素首剂1000 U,持续500 U/h量不变;观察组患者肝素首剂1000 U,初始维持量500 U/h,随后每4 h调整一次肝素用量;对比2组患者的治疗效果.结果 观察组治疗时间(23.73±18.97)h明显高于对照组(16.28±10.74)h(P<0.05);观察组滤器凝血例数明显少于对照组(P<0.05).结论 在连续性血液净化中调整普通肝素剂量能够延长治疗时间,提升治疗效果,延长滤器寿命.
Application and nursing of unfractionated heparin dose adjustment in continuous blood purification
Objective To explore the application effect and nursing measures of unfractionated heparin dose adjustment in continuous blood purification. Methods From January 2014 to January 2017 in Huzhou Central Hospital, 94 patients of continuous blood purification treatment according to the time sequence, were divided into observation group (n=47) and control group (n=47), all patients were treated by continuous blood purification treatment, the control group of heparin in patients with an initial dose of 1000 U, continuous 500 U/h constant patients in the observation group;the first dose of heparin 1000 U, initial maintenance dose of 500 U/h, then each 4 h adjusted once the amount of heparin; compared two groups of patients. Results The observation group treatment time (23.73±18.97) h was significantly higher than the control group (16.28±10.74) h, significant difference (P<0.05); filter clotting in observation group were significantly less than the control group, there was statistical significance (P<0.05). Conclusion Adjusting the dose of unfractionated heparin in continuous blood purification can prolong the treatment time, improve the treatment effect and prolong the life of filter.

heparincontinuous blood purificationtreatment time

吴辰、朱云

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湖州市中心医院 212病区,浙江 湖州 313000

肝素 连续性血液净化 治疗时间

2017

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
年,卷(期):2017.37(11)
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