质子泵抑制剂治疗消化性溃疡致白细胞减少的临床探讨
Clinical study of proton pump inhibitor in the treatment of leukopenia caused by peptic ulcer
杨宝华 1许智利 1林强康 1陈玲珑1
作者信息
- 1. 温州市人民医院 急诊科,浙江 温州 325000
- 折叠
摘要
目的 分析消化性溃疡对机体白细胞计数的影响并探讨质子泵抑制剂对此情况的改善作用.方法 分别对研究组消化性溃疡患者、对照组健康人群给予白细胞计数检验,待研究组患者临床对症治疗完成后再次对其机体白细胞计数予以检验.记录研究组治疗前后、对照组白细胞计数检验结果,将所得数据输入SPSS软件后给予相应分析并得出结论.结果 研究组消化性溃疡患者白细胞计数水平显著低于对照组健康人群(P<0.05).研究组消化性溃疡患者治疗后白细胞计数水平较治疗前显著上升(P<0.05).结论 消化性溃疡对机体白细胞计数具有一定影响效果,利用质子泵抑制剂对消化性溃疡患者病情具有较好的改善效果,有利于提高白细胞计数水平.
Abstract
Objective To analyze the effect of peptic ulcer on the white blood cell (WBC) count and to investigate the effect of proton pump inhibitors on this condition. Methods The patients with peptic ulcer in the study group and healthy people in the control group were given the WBC count, the WBC count of the patients in the study group were tested again after the clinical symptomatic treatment was completed. The results of WBC the study group before and after treatment were recorded, the data were input into the SPSS software to give the corresponding analysis and draw conclusions. Results The WBC count of the peptic ulcer patients in the study group was significantly lower than that of the healthy people in the control group (P<0.05); the WBC count of the study group after peptic ulcer treatment was increased significantly compared with before treatment (P<0.05). Conclusion Peptic ulcer has a certain effect on the WBC count, and the application of proton pump inhibitors could improve the condition of patients with peptic ulcer, and was conducive to improve the level of WBC count.
关键词
质子泵抑制剂/消化性溃疡/白细胞计数/埃索美拉唑Key words
proton pump inhibitors/peptic ulcer/white blood cell count/esomeprazole引用本文复制引用
出版年
2017
NETL
NSTL
维普
万方数据