Prenatal biochemical screening methods and results of thalassemia
Objective To observe and analyze the methods and results of prenatal biochemical screening for thalassemia. Methods 2000 pregnant women who underwent prenatal screening and delivery in our hospital were selected from May 2014 to May 2017. The clinical data of pregnant women were collected and analyzed retrospectively. Results By means of prenatal biochemical screening test, 23 cases of thalassemia were detected in all pregnant women, and the incidence rate was 1.15%. Moreover, in these cases, the level of beta -HCG was above 2.5mmol/L, the concentration of AFP was below 0.3mmol/L, and the level of PAPP-A was below 0.5mmol/L. Moreover, the number of cases of alpha thalassemia and beta thalassemia was 5 and 18 respectively. Compared with normal pregnant women, cases of alpha thalassemia and beta thalassemia were lower, MCH and MCV were lower, and RDM was significantly higher(P<0.05). Conclusion Through the implementation of prenatal biochemical screening test measures, can be timely detection of cases of thalassemia pregnant women, and can effectively improve the eugenic ratio.
NETL
NSTL
万方数据
维普
