目的 探讨新生儿早发型B族链球菌(group B streptococcus,GBS)感染的预防治疗及护理方法.方法 回顾性分析杭州市妇产科医院新生儿科在2016年1月~2016年12月收治的204例符合新生儿早发型GBS感染预防治疗的患儿临床资料,总结其早期干预方法.结果 本组患儿治愈185例(90.7%);好转17例(8.3%);无效并转院2例(1.0%).出院1 w后随访共193例,191例喂养及生长发育良好;2例合并化脓性脑膜炎死亡.结论 以青霉素为首选药物的预防治疗和综合护理措施,并以细致的病情观察和加强皮肤黏膜护理为重点,同时加强无菌操作及营养护理,可促进高危早发型GBS感染新生儿的康复,防止病情恶化,效果满意.
Early interventionfor early onset of neonatal group B streptococcal infection
Objective To review the evidence and to provide recommen-dations on the management of the preventionfor the early-onset neonatal group B streptococcal disease. Methods We reviewed and analyzedthe data from atotal of 204 cases of neonatesmet the standards for early onset neonatal GBS infection preventive treatment in our hospital between 1st January and 31th December 2016, and summarized the preventive measures. Results The cure rates, the improvement rates and the invalid rates were 90.7%, 8.3% and 1.0%, respectively. We followed 193 cases 1 week after discharge, 191 cases had good growth and 2 cases died of suppurative meningitis. Conclusion The preventive treatment of penicillin as the preferred drug and comprehensive care measures, to observe thedelicate condition, strengthen the skin and mucous membrane care as the focus and the concept of aseptic care and nutrition care, can lead to the rehabilitation and the prevention of the disease deteriorationof the high risk of early-onset GBS infection in neonates.