摘要
目的 分析多次单采血小板献血者外周血象部分参数变化.方法 随机选取义乌市中心血站2014年4月~2017年4月连续捐献的血小板献血者215例的血检报告,其中总捐献次数5次及以上的215例,10次以上208例、15次以上185例、20次以上75例、30次以上35例.根据献血者的捐献次数,分别统计其首次、第6次、第11次、第16次、第21次、第31次捐献前的外周血象参数,并将首次捐献前与末次捐献前的参数进行对比分析.结果 与首次捐献前比较,捐献血小板5次后献血者的MCV,捐献血小板10次后献血者的WBC、PDW、MPV,捐献血小板15次后献血者的RBC、Hct、PLT、WBC,捐献血小板20次后献血者的Hb、Hct、MCV、WBC、PLT、MPV,捐献血小板30次后献血者的Hct、MCV、WBC、PLT、MPV参数差异有统计学意义(P<0.05);其他各项指标差异均无统计学意义.结论 长期多次捐献血小板会引起献血者红细胞压积、红细胞平均体积、白细胞计数、血小板计数、血小板平均体积的减少、血红蛋白的增加,体检时应注意这些参数,保障献血者的身体健康.
Abstract
Objective To analyze the changes of peripheral blood parameters in single platelet donors of many times. Methods A total of 215 blood samples were collected from Yiwu blood center from April 2014 to April 2017. There were 215 donors with 5 times and more donations, 208 donors with ten times and more donations, 185 donors with 15 times and more donations, 75 donors with 20 times and more donations, and 35 donors with 30 times and more donations. According to the times of donations, the statistics of the peripheral blood samples the first donation, the sixth donation, the 11th donation, the 16th donation, the 21st donation and the 31st donation were counted, and the parameters before the last donation were compared and analyzed. Results This study suggested that compared with before the first donation, there were significant difference in the donor blood MCV after the blood donation of 5 times; the blood donors of the WBC, PDW, MPV after donated platelet 10 times; the donor RBC, Hct, PLT after donated platelet 15 times, the donor Hb、Hct、MCV、WBC、PLT、MPV after donated platelet 20 times, and the donor Hb、Hct、MCV、WBC、PLT、MPV after donated platelet 30 times (P<0.05). The other indicators were not statistically significant. Conclusion Long-term donation of platelets could lead to reduce hematocrit, red blood cell mean volume, white blood cell count, platelet count, platelet mean volume and increase Hb, in physical examination these parameters should be paid attention to protect the health of blood donors.
基金项目
浙江省2015年省医药卫生一般研究计划项目(2015KYA089)
NETL
NSTL
维普
万方数据