耐甲氧西林金黄色葡萄球菌联合用药的效应
Effect of methicillin-resistant staphylococcus aureas combination therapy
李晔 1张寅英1
作者信息
- 1. 嘉兴市妇幼保健院 药剂科,浙江 嘉兴 314051
- 折叠
摘要
MRSA感染已成为临床感染治疗中亟待解决的难题,而单用药治疗MRSA感染又存在诸多局限,本文从MRSA的耐药现状与机制、抗菌药物单用与联用对MRSA的抗菌活性及临床对MRSA的治疗策略等方面进行综述,旨在为临床合理选择药物及减少细菌耐药提供参考.
Abstract
In recent days, serious infection caused by MRSA has become a burning issue that must be sloved in the clinical treatment. However, there are many limitations in the treatment against MRSA using single drug. In this review, we discuss from the following aspects: the current status and mechanism of drug resistance against MRSA, the antibacterial activity against MRSA by using single antimicrobial agents or in combination, as well as treatment strategies against MRSA. The aim is to provide reference for rational use of antimicrobials and reduce drug resistance.
关键词
联合用药/耐甲氧西林金黄色葡萄球菌/MRSA/治疗策略Key words
drug combination/methicillin-resistant staphylococcus aureus/MRSA/treatment strategy引用本文复制引用
基金项目
嘉兴市科技计划项目(Z2014AY21047)
出版年
2017