中国神经精神疾病杂志2024,Vol.50Issue(9) :560-564.DOI:10.3969/j.issn.1002-0152.2024.09.008

脑电技术在抑郁症非自杀性自伤行为和自杀意念中研究进展

Advance in research on EEG technology in non-suicidal self-injurious behaviour and suicidal ideation in de-pression

何宇航 易芸 李荷花 吴逢春 江帆 吴凯 黄园园
中国神经精神疾病杂志2024,Vol.50Issue(9) :560-564.DOI:10.3969/j.issn.1002-0152.2024.09.008

脑电技术在抑郁症非自杀性自伤行为和自杀意念中研究进展

Advance in research on EEG technology in non-suicidal self-injurious behaviour and suicidal ideation in de-pression

何宇航 1易芸 2李荷花 3吴逢春 3江帆 3吴凯 4黄园园3
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作者信息

  • 1. 广州医科大学附属脑科医院精神科(广州 510370)
  • 2. 广西壮族自治区脑科医院精神科
  • 3. 广州医科大学附属脑科医院精神科(广州 510370);广东省精神疾病转化医学工程技术研究中心;广东省神经科学疾病研究重点实验室
  • 4. 华南理工大学
  • 折叠

摘要

非自杀性自伤行为和自杀意念是抑郁症患者自杀未遂的重要危险因素.目前研究发现,两者在脑电特征上存在明显差异.脑电静息态分析发现伴自杀意念抑郁症患者Gamma绝对功率在特定电极点明显升高,伴非自杀性自伤行为者的Beta和Gamma活性发生变化.脑电微状态研究表明,伴非自杀性自伤行为者、伴自杀意念者的微状态存在差异,其中微状态序列短片段具有一定潜力.事件相关电位研究中,两者在P3波、N2波等成分表现出特定特征,伴非自杀性自伤行为的抑郁症患者N2波幅值较低.虽然脑电技术的机器学习相关研究较少,但已显示出一定的应用前景.因此本文概述两者相关的脑电研究进展,旨在为抑郁症自杀的早期预测提供依据.

Abstract

Non-suicidal self-injury behavior and suicidal ideation are important risk factors for suicide attempts in patients with depression.At present,studies have found that there are obvious differences in electroencephalogram(EEG)characteristics between these two.Resting-state EEG analysis reveals that the absolute power of Gamma in specific electrode points is significantly increased in patients with depression accompanied by suicidal ideation.The Beta and Gamma activities of those with non-suicidal self-injury behavior changed.EEG microstate research shows that there are differences in microstates between those with non-suicidal self-injury behavior and those with suicidal ideation.Among them,short segments of microstate sequences have certain potential.In event-related potentials,these two show specific characteristics in components such as P3 wave and N2 wave.The amplitude of N2 wave in patients with depression accompanied by non-suicidal self-injury behavior is lower.Although there are few machine learning-related studies on EEG technology,it has shown certain application prospects.Therefore,this article will summarize the progress of EEG research related to the two,aiming to provide a basis for early prediction of suicide in depression.

关键词

抑郁症/自我伤害行为/自杀意念/自杀/脑电图/事件相关电位/机器学习

Key words

Depression/Self-injurious behaviour/Suicidal ideation/Suicide attempt/EEG/Event-related po-tentials/Machine learning

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基金项目

国家自然科学基金(82301688)

广东省医学科学技术研究基金项目(A2023224)

广州市科技计划项目(202201010093)

广州市科技计划项目(202206010077)

广州市科技计划项目(2023A03J0856)

&&(2023YQJK438)

出版年

2024
中国神经精神疾病杂志
中山大学

中国神经精神疾病杂志

CSTPCD北大核心
影响因子:1.38
ISSN:1002-0152
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