目的 探讨多系统萎缩(multiple system atrophy,MSA)患者并发尿潴留的临床特征以及发生尿潴留的影响因素.方法 纳入2021年9月至2022年12月于北京中医药大学东方医院门诊就诊的MSA患者100例,根据膀胱残余尿量将患者分为无尿潴留组(残余尿量＜100 mL)和尿潴留组(残余尿量≥100 mL),分析两组患者间性别、年龄、受教育年限、既往病史、病程、临床分型、临床诊断等级、直立性低血压、卧位高血压、性功能障碍以及相关量表评分差异.采用二元Logistic回归筛选影响MSA患者发生尿潴留的危险因素.结果 MSA患者发生尿潴留47例(47.0％).与无尿潴留组比较,尿潴留组很可能的MSA患者占比更高(P＜0.05),统一MSA评分量表(UMSARS)-Ⅰ、日间尿频、尿急、急迫性尿失禁评分均更高(均P＜0.05).急迫性尿失禁是MSA患者发生尿潴留的独立危险因素(OR=1.995,P=0.010).结论 MSA患者发生尿潴留较为普遍,其中急迫性尿失禁是MSA伴发尿潴留的独立危险因素.
Clinical characteristics and risk factors of urinary retention in patients with multiple system atrophy
Objective To explore the clinical characteristics and the influencing factors of urinary retention in patients with multiple system atrophy(MSA).Methods One hundred cases of patients with MSA who attended the outpatient clinic of Dongfang Hospital of Beijing University of Traditional Chinese Medicine from September 2021 to December 2022 were included.The patients were divided into the group with no urinary retention(residual urine＜100 mL)and the group with urinary retention(residual urine≥100 mL),according to the amount of bladder residual urine.The differences in gender,age,years of education,past medical history,duration of disease,clinical type,clinical diagnostic grade,orthostatic hypotension,recumbent hypertension,sexual dysfunction and scores on relevant scales were analyzed.Binary Logistic regression was used to screen the risk factors of urinary retention in MSA patients.Results Forty-seven cases(47.0％)of MSA patients had urinary retention.Compared with the group without urinary retention,the proportion of probable MSA patients in the urine retention group was higher(P＜0.05),and the unified MSA score scale(UMSARS)-Ⅰ,daytime frequency of urination,urgency of urination and urge incontinence scores were higher(all P＜0.05).Urge incontinence score was an independent risk factor for urinary retention in MSA patients(OR=1.995,P=0.010).Conclusions Urinary retention is common in MSA patients,and urge incontinence is an independent risk factor for MSA with urinary retention.
multiple system atrophyurinary retentionclinical characteristicsrisk factors
万方数据
维普
