To investigate the effects of adding different levels of yeast feed additives on the growth performance,nutrient apparent digestibility,and blood biochemical indicators of weaned piglets.This experiment selected with similar age and a weight of 21±0.5 kg 120"big×long×large"three way hybrid weaned piglets were randomly divided into 4 groups according to the experimental design.Each experimental group was divided into 3 replicate groups,with 10 piglets in each replicate"big×long×large"three way hybrid weaned piglets were divided into 0(control group),1.0%,2.0%,and 3.0%yeast feed additive groups.The pre experiment for experimental feeding was 10 days,and the entire experimental period was 60 days.The results showed that:1)The average daily gain of the 2.0%and 3.0%yeast feed additive groups was significantly increased by 15.5%and 15.9%compared to the control group(P<0.05),and their feed weight was significantly reduced by 12.6%and 12.6%compared to the control group(P<0.05);2)The apparent digestibility of crude protein and crude fiber nutrients in feces of the 2.0%and 3.0%yeast feed additives groups was significantly increased by 11.2%,12.1%,12.9%,and 15.7%compared to the control group,respectively(P<0.05);3)The levels of TP and GLB in the serum of the 2.0%and 3.0%yeast feed additives groups were significantly increased by 17.2%,17.6%,21.0%,and 22.3%compared to the control group(P<0.05),respectively.The levels of AST and BUN in the serum were significantly reduced by 18.7%,18.7%,10.7%,and 12.0%compared to the control group(P<0.05).In summary,adding 2.0%yeast feed additives can effectively improve the growth performance and nutrient apparent digestibility of piglets,improve blood biochemical indicators,and can be promoted and applied in production.