Effects of mannan oligosaccharides on growth performance,immune function and antioxidant performance of weaned piglets
In order to study the effects of Mannan oligosaccharides on growth performance,immune function and antioxidation of weaned piglets,160 healthy 30-day-old weaned piglets were randomly divided into 4 treatments with 5 replicates per treatment and 8 piglets per replicate.The control was the basic diet,and the experimental groups T1,T2 and T3 were supplemented with 100 mg/kg chlortetracycline,0.1%mannan-oligosaccharide and 0.2%mannan-oligosaccharide respectively for 28 days.The results showed that the average daily gain of weaned piglets supplemented with 0.1%,0.2%and 0.4%Mannan oligosaccharides was significantly higher than that of the control by 8%,14%and 13%,respectively.The ratio of feed to gain decreased by 7%,10%and 9%respectively,and the diarrhea rate decreased by 39.2%,32.7%and 37%respectively.But it did not affect the feed intake of weaned piglets.The contents of IgG,IgA,IgM,CD3+,CD4+ and CD8+ in the blood of weaned piglets treated with Mannan oligosaccharides were significantly higher than those in the control group,and 0.2%Mannan oligosaccharides had the best effect.Compared with the control group,the contents of IgG,IgA,IgM,CD3+,CD4+ and CD8+ in the control group were significantly increased by 33.9%,57.8%,16.3%,19.3%,45.6%and 15.3%,respectively.The ratio of CD4+ and CD8+ is closest to 2,that is,the maximization of immune function.The antioxidant capacity of weaned piglets was improved by adding different proportions of Mannan oligosaccharides,among which 0.2%Mannan oligosaccharides had the best effect.The activities of SOD and GSH-Px in the blood of weaned piglets were significantly higher than those of the control group,and the content of MDA was significantly lower than that of the control group.The results showed that the addition of Mannan-oligosaccharide could improve the growth performance,blood immune function and antioxidant capacity of weaned piglets,and 0.2%of them had better effect.