Effects of glutamine supplementation on growth performance,serum immunity,and antioxidant indicators in weaned piglets
The aim of this study is to investigate the effects of glutamine supplementation on the growth performance,serum immunity,and antioxidant indicators of weaned piglets.The experiment randomly divided 400 ternary hybrid piglets with good growth and health status and similar body weight into 4 groups,with 10 replicates in each group,with 10 piglets in each replicate.Add 0%,0.5%,1.0%,and 2.0%glutamine to the basic diet as the experimental feed.The experiment lasted for a total of 42 days(pre test for 7 days and trial for 35 days).The experimental results showed that Compared with the control group,the feed supplemented with 1%and 2%glutamine increased the final body weight of piglets by 8%and 8%,respectively(P<0.05),and the average daily gain increased by 12%and 11%,respectively(P<0.05).The feed to weight ratio decreased by 10%and 9%,respectively(P<0.05).In addition,the feed supplemented with glutamine had no significant effect on the average daily feed intake of piglets(P>0.05).The addition of 1%and 2%glutamine to the diet significantly increased the serum IgA,IgM,and IgG content of piglets(P<0.05),while the addition of glutamine to the diet significantly increased the serum IL-10 content of piglets(P<0.05).In addition,the addition of glutamine to the diet affected the serum IL-1 levels in piglets β、IL-6 and TNF-α There was no significant impact(P>0.05).Adding glutamine to the diet significantly increased the serum CAT,GPX,and Cu Zn SOD activities of piglets(P<0.05),with the highest activity in the 1%addition group(P<0.05).Adding glutamine to the diet significantly reduced the serum MDA content of piglets(P<0.05).In addition,adding glutamine to the diet had no significant effect on the serum T-SOD activity of piglets(P>0.05).In summary,under the conditions of this experiment,the optimal amount of glutamine added to the diet of piglets is 1%.