Effects of astragalus polysaccharides on growth performance,immunity,and serum biochemical indicators in broilers
The aim of this experiment is to investigate the effects of dietary addition of aflatoxin on growth performance,serum biochemical and immune indicators in broilers.1000 healthy and growing white feather broilers were randomly divided into 4 groups,with 10 replicates in each group,with 25 chickens per replicate.Add 0,40,80,and 160μg/kg of aflatoxin B1 to the basic diet as the experimental feed.The experiment lasted for a total of 42 days.The experimental results showed that without significant differences in initial body weight(P>0.05),adding 80 and 160μg/kg of aflatoxin B1 to the diet significantly reduced the final body weight of broilers by 2.8%and 6.9%,respectively(P<0.05);Adding 160μg/kg of aflatoxin B1 to the diet significantly reduced the average daily gain of broilers by 7.1%(P<0.05)and the average daily feed intake by 5.2%(P<0.05).Adding 160μg/kg of aflatoxin B1 to the diet significantly reduced the thymus index of broilers(P>0.05).In addition,adding aflatoxin B1 to the diet had no significant effect on the spleen index and bursal index of broilers(P>0.05).Adding 80 and 160μg/kg of aflatoxin B1 to the diet significantly reduced the serum IgA and IgM levels in broilers(P<0.05);In addition,the addition of aflatoxin B1 to the diet had no significant effect on the serum IgG and serum amyloid A content of broilers(P>0.05).Adding 80 and 160μg/kg of aflatoxin B1 to the diet significantly reduced the total serum protein and albumin content of broilers(P<0.05);Adding 80 and 160μg/kg of aflatoxin B1 to the diet significantly increased the activities of serum alanine aminotransferase and alanine aminotransferase in broilers(P<0.05);In addition,the addition of aflatoxin B1 to the diet had no significant effect on the serum globulin content of broiler chickens(P>0.05).In summary,the results of this experiment indicate that adding 160μg/kg of aflatoxin B1 to the diet inhibits the growth and development of broilers by negatively regulating serum biochemical and immune indicators.