Effects of Callicarpa nudiflora Hook on growth performance and intestinal health of broilers
In order to explore the effects of different doses of CH on broiler production performance,intestinal antioxidant capacity and intestinal barrier function,a total of 240 1-day-old broiler were randomly assigned to 4 groups with 4 replicates per group and 15 birds per replicate.Broilers were fed a basal diet(control group),the basal diet supplemented with 1,3,5 g/kg CH from 1～28 days of ages.The results showed as follows:(1)The average daily weight gain and average feed intake in the CH-3 group increased by 7.2％and 11.9％compared with the CON group(P＜0.05).(2)The broiler bursal index and the content of serum immunoglobulin M(IgM)in the CH-1 group increased by 48.8％and 16.6％compared with the CON group(P＜0.05);the content of serum immunoglobulin G(IgG)in the CH-1 and CH-3 group increased by 11.2％and 12.4％compared with the CON group(P＜0.05).(3)The content of serum malondialdehyde(MDA)in the CH-1 group was reduced by 22.4％(P＜0.05)compared with the CON group;the levels of serum superoxide dismutase(SOD)in the CH-1 group increased by 12.7％(P＜0.05).(4)The ileum villus height and the ratio of ileum villus height to crypt depth in the CH-1 group increased by 19.1％and 18.6％compared with the CON group(P＜0.05);(5)The gene expression levels of GLUT-2,GSH-Px,ZO-1,Occludin-1,IL-4 and IL-10 in ileum mucosa in CH-1 group increased by 41.0％,32.4％,39.6％,38.5％,23.8％and 38.0％compared with the CON group(P＜0.05);the gene expression levels of Claudin in ileum mucosa in CH-3 group increased by 62.4％compared with the CON group,the gene expression levels of MyD88 in ileum mucosa in the CH-3 group decreased by 14.5％compared with the CON group,the gene expression levels of superoxide dismutase(SOD 1)and cationic amino acid transporter protein(CAT)in ileum mucosa in the CH-5 group increased by 39.4％and 48.5％compared with the CON group(P＜0.05);The expression of Nrf2 in ileum mucosa increased by 39.4％,30.3％,respectively,in all dose group compared with the CON group(P＜0.05).In conclusion,under the condition of this experiment,supplementation of 1 mg/kg CH could significantly improve growth performance,enhance the status of antioxidant function and immune,promote intestinal villi development,improve intestinal integrity.
Callicarpa nudiflora HookHainan Wenchang broilergrowth performanceantioxidant functionimmune function
万方数据
维普
