The effects of Clostridium butyricum on the growth performance,serum biochemical indicators,and immune indicators of weaned piglets
Explore the effects of Clostridium butyricum(CB)on the growth performance,serum biochemical indicators,and immune indicators of weaned piglets.200 healthy hybrid piglets with an initial weight of 8.14±0.07kg and similar age were randomly divided into 4 groups of 5 replicates with 10 replicates each.separately.Add 0,1,5,and 10 to the base diet separately×109 CFU/kg of Clostridium butyricum was used as the experimental diet.The experiment lasted for 35 days.Feed addition 1~10×108 CFU/kg Clostridium butyricum significantly increased the average daily weight gain of piglets in the treatment group by 4.8%,6.65%,and 7.4%,respectively(P<0.05);Feed addition 1~10×108 CFU/kg Clostridium butyricum significantly reduced the average daily feed intake of piglets in the treatment group by 2.9%,5.2%,and 4.6%,respectively(P<0.05);Feed addition 1~10×108 CFU/kg Clostridium butyricum significantly reduced the feed to weight ratio of piglets in the treatment group by 7.4%,11%,and 11.2%,respectively(P<0.05);In addition,the addition of Clostridium butyricum to the diet had no significant effect on the final body weight of piglets(P<0.05).Feed addition 5~10×108 CFU/kg Clostridium butyricum significantly increased the total serum protein content of piglets(P<0.05),and significantly reduced the serum urea nitrogen and triglyceride content of piglets(P<0.05);Feed addition 5×108 CFU/kg Clostridium butyricum significantly increased the serum albumin content of piglets(P<0.05);In addition,Clostridium butyricum had no significant effect on the levels of serum albumin,glucose,and total cholesterol in piglets(P>0.05).Feed addition 5~10×108 CFU/kg Clostridium butyricum significantly increased the serum IgA and IgM levels in piglets(P<0.05);Feed addition 5×108 CFU/kg Clostridium butyricum significantly increased the serum IL-2 content in piglets(P<0.05);Feed addition 1~10×108 CFU/kg Clostridium butyricum significantly reduces serum IL-1 in piglets β Content(P<0.05);Feed addition 5×108 CFU/kg Clostridium butyricum significantly increased the serum IL-10 content in piglets(P<0.05);In addition,Clostridium butyricum has effects on serum IgG,IL-6,and TNF in piglets-α The content had no significant effect(P>0.05).In summary,under the conditions of this experiment,5×The addition of 108 CFU/kg Clostridium butyricum has the best growth promoting effect.