Effects of sodium butyrate on growth performance,intestinal antioxidant indicators,and intestinal morphology in meat rabbits
The aim of this study was to investigate the effects of adding sodium butyrate to the diet on the growth performance,intestinal antioxidant indicators,and morphological structure of meat rabbits.600 30 day old weaned rabbits were randomly divided into 4 groups,with 5 replicates in each group and 30 rabbits in each replicate.Add 0.00%,0.05%,0.10%,and 0.20%sodium butyrate to the basic feed as the experimental feed.The experiment lasted for a total of 42 days.The experimental results showed that compared with the control group,adding 0.1%～0.2%sodium butyrate significantly increased the final body weight of meat rabbits by 8.98%and 9.55%(P＜0.05),and the average daily weight gain was significantly increased by 14.41%and 12.71%(P＜0.05).The average daily feed intake was significantly increased by 7.26%and 5.80%(P＜0.05),and the feed to weight ratio was significantly reduced by 6.24%and 6.13%(P＜0.05),respectively.Compared with the control group,adding sodium butyrate to the diet significantly increased CAT activity in the duodenum of meat rabbits(P＜0.05);The addition of 0.05%and 0.2%sodium butyrate significantly increased the GSH Px activity in the jejunum of meat rabbits(P＜0.05);The addition of 0.1%sodium butyrate significantly increased the T-SOD,GSH Px,and CAT activities in the ileum of meat rabbits(P＜0.05);In addition,adding sodium butyrate to the diet had no significant effect on T-SOD activity in the duodenum and jejunum of meat rabbits(P＞0.05).After adding 0.2%sodium butyrate to the diet,the height and V/C value of duodenal villi in meat rabbits were significantly higher than those in the control group(P＜0.05);After adding 0.05%～0.2%sodium butyrate to the feed,the villus height and V/C value of the ileum in meat rabbits were increased to varying degrees(P＜0.05);In addition,adding sodium butyrate to the diet had no significant effect on the crypt depth of each intestinal segment in meat rabbits(P＞0.05).In summary,sodium butyrate can enhance the antioxidant enzyme activity and improve the intestinal morphology of meat rabbits.Under the experimental conditions,the optimal amount of sodium butyrate added to the diet of meat rabbits is 0.1%.
万方数据
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