Meta-analysis of the effect of herbal feed additives on stress syndrome in weaned piglets
To study the effect of herbal feed additives on stress syndrome in weaned piglets and to provide a reference for finding alternatives to antibiotics.In this study,relevant randomized controlled trials(RCTs)published from January 2011 to January 2023 in four databases,China Knowledge,Wanfang Data,Pubmed,and Science Direct,were searched by computer,and statistical analysis was performed using a random effects model with Review Manger 5.4 software using Meta-analysis and calculating the mean difference(MD)with 95％confidence intervals,and finally,the publication bias of the included literature was analyzed.The results of the Meta-analysis showed that,compared with the control group,the various types of herbal feed additives were able to significantly increase the average daily weight gain(17.6％,P＜0.01),average daily feed intake(6.8％,P＜0.01)and total protein in the blood(13.7％,P＜0.01)of weaned piglets,blood immunoglobulin content(12.5％increase in immunoglobulin A,15.1％increase in immunoglobulin G,and 10.0％increase in immunoglobulin M,P＜0.01)and a highly significant reduction in the feed-to-weight ratio(10.9％,P＜0.01)and diarrhea rate(55.2％,P＜0.01).The included literature had some publication bias but the degree of bias was low and the sensitivity analysis was more reliable.This suggested that herbal feed additives have the potential to replace antibiotics to alleviate stress syndrome in weaned piglets.
万方数据
维普
