The aim of this study was to investigate the effects of Poria cocos extract on serum biochemical indexes and lipid metabolism of meat rabbits.A total of 400 healthy 30-day-old weaned rabbits were randomly divided into 4 groups with 10 replicates per group and 10 rabbits per replicate.The experimental diet was supplemented with 0%,0.05%,0.1%and 0.2%poria polysaccharides in the base diet,respectively,and the experiment lasted for 42 days(pre-feeding period was 5 days and experimental period was 37 days).The results showed that dietary supplementation of 0.2%poria cocos extract could significantly increase the contents of serum total protein and albumin of meat rabbits(P＜0.05).Dietary supplementation of 0.1%and 0.2%poria cocos extract significantly decreased serum triglyceride content(P＜0.05),and significantly increased serum insulin content and alanine aminotransferase activity of meat rabbits(P＜0.05).However,there were no significant effects on serum leptin and very low density lipoprotein contents and the activities of alkaline phosphatase and ASpartate transaminase in meat rabbits(P＞0.05).Dietary addition of poria cocos extract significantly decreased the percentage of shoulder fat and kidney fat(P＜0.05),but had no significant effect on the percentage of pericardial fat in meat rabbits(P＞0.05).The foreleg muscle percentage and hind leg muscle percentage of meat rabbits in 0.1%and 0.2%supplementation groups were significantly increased(P＜0.05).0.2%supplementation group significantly increased the expressions of CPT-1,CPT-2 and PPAR-α genes in liver of meat rabbits(P＜0.05),but had no significant effects on the expressions of FAS and ACC genes(P＞0.05).In conclusion,the results of this experiment showed that dietary supplementation of Pachycoia extract could enhance lipolysis and promote the growth and development of meat rabbits.
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