Effects of fermentation broth of complex probiotic on the milk composition,immune function,and milk-borne hormone in late gestation sows
This experiment was conducted to investigate the effects of different dose fermentation broth of complex probiotic on the composition,immune function and hormone indexes of sow colostrum.A total of 48 healthy binary sows(Landrace × Large White)were randomly divided into 4 groups,with 12 repetitions per group,they were the control group(fed a basic diet),and experimental groups Ⅰ,Ⅱ,and Ⅲ(the experimental groups Ⅰ,Ⅱ,and Ⅲ were added 150,300,450 mLld fermentation broth of complex probiotic to the basic diet,respectively).The experiment was conducted on the day 85 of gestation and lasted until the day 7 of postnatal,with no addition of fermentation broth of complex probiotic after delivery.The results showed as follows:(1)Changes in milk composition:After adding complex probiotic fermentation broth to the diet,the milk protein of experimental group Ⅱ and the milk fat of experimental group Ⅲ in colostrum were significantly higher than those of control group(P<0.05);the milk protein of experimental group Ⅱ and the milk total solids of experimental group Ⅲ in milk were significantly higher than those of control group(P<0.05);(2)Changes in immune indexes of milk:After adding complex probiotic fermentation broth to the diet,compared with control group,the contents of IL-2 and IL-6 in colostrum of experimental group Ⅱ were significantly lower(P<0.05);The contents of IgA,IgG and IgM in colostrum of experimental group Ⅲ were significantly higher(P<0.05),however,there was no significant difference compared with the experimental group Ⅱ;In normal milk,the content of IL-2 in experimental group Ⅱ was significantly decreased,while the contents of IgA and IgG were significantly increased.(3)Changes of hormone indexes in milk:After adding complex probiotic fermentation broth to the diet,the contents of PRL and IGF-1 in experimental group Ⅱ and GH in experimental group Ⅲ of colostrum were significantly higher than those in the control group(P<0.05);In normal milk,PRL in experimental group Ⅱ and GH and IGF-1 in experimental group Ⅲ were significantly higher than those in control group(P<0.05).In conclusion,fermentation broth of complex probiotic supplementation in late gestation could improve the milk composition of colostrum and normal milk,increase the content of immunoglobulin and hormones in milk,thereby,enhancing the body immunity of piglets and promoting their growth,and the adding 300 mL/d was recommended.
fermentation broth of complex probioticlate-gestation sowsmilk compositionimmune function of milkmilk-borne hormone changes