The effects of high-fat feed on growth performance,obesity indicators,and endurance training in mice
Objective:To investigate the effects of high-fat feed on growth performance,obesity indicators,and endurance training in mice.Method:160 KM mice around 2 weeks old with similar initial weight[(8.16±0.23)g]were selected(♂),Randomly divide into 2 groups,with 4 replicates in each group,and 20 replicates in each group.Two groups were fed with conventional feed and high-fat feed respectively,and the conventional feed was configured according to the Nutrition Composition of Experimental Animal Formula Feed(GB 14924.3-2010).The experiment lasted for 42 days,during which all mice were free to feed and drink water.Result:(1)Compared with the conventional feed group,the final weight of the high-fat feed group mice significantly increased by 24.48% (P＜0.05),the average daily weight gain significantly increased by 31.51% (P＜0.01),and the feed to weight ratio significantly decreased by 22.38% (P＜0.05).(2)Compared with the conventional feed group,the Lee's index of mice in the high-fat feed group was significantly increased by 9.73(P＜0.05),BMI index was significantly increased by 29.48% (P＜0.01),and body fat percentage was significantly increased by 132.77% (P＜0.01).(3)Compared with the conventional feed group,the weight-bearing swimming time of mice in the high-fat feed group was significantly reduced by 17.09% (P＜0.05).Conclusion:This experiment found that compared with conventional feed,high-fat feed not only improved the growth performance of mice,but also led to obesity and decreased endurance,providing data reference for the study of high-fat induced obesity.
high fat feedmicegrowth performanceobesity indicatorsendurance training
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