Progress in research and application of bacteriocins
Bacteriotin is a class of protein or peptide substances with antibacterial effect produced by bacteria in the metabolic process,which can inhibit the growth and reproduction of most gram-positive bacteria and gram-negative bacteria.It has good biological characteristics such as non-toxic,easy to be hydrolyzed by various enzymes,easy to produce drug resistance,and strong stability.It can be used in food storage,medicine,animal breeding and other aspects,and has the ability to replace chemical preservatives and the potential to alleviate antibiotic resistance.This paper reviewed the research status of bacteriocins,their categories,differences from antibiotics,antibacterial mechanism,biosynthesis mechanism,fermentation strains,production methods,and application status in food,medicine,animal breeding and other aspects,and summarized a series of problems in the development process of bacteriocins,such as low yield,poor effect,and vulnerable stability.At the same time,the possible solutions to these problems were proposed to provide help for the development and utilization of bacteriocins.