The effects of fermented beer lees on the growth performance,intestinal morphology,and expression of inflammatory factor genes in broiler chickens
The aim of this study is to investigate the effects of fermented beer lees(FBL)on the growth performance,intestinal morphology,and expression of inflammatory factor genes in broiler chickens.1800 1-day-old white feathered broiler chickens were randomly divided into 4 groups,with 1 group consisting of 9 replicates and 1 replicate consisting of 50 chickens.Add 0%,3%,6%,and 9%FBL as experimental feed for a total of 42 days.FBL has a significant impact on the growth performance of broiler chickens.The addition of 9%FBL significantly reduced the average daily gain(ADG)of broiler chickens by 2.77%(P＜0.05),and the feed to meat ratio(F/G)significantly increased by 6.90%(P＜0.05).9%of FBL group broiler chickens showed a significant increase in duodenal crypt depth(P＜0.05)and a significant decrease in V/C value(P＜0.05);The ileal crypt depth of broiler chickens in the 6%and 9%FBL groups significantly increased(P＜0.05).6%and 9%FBL groups of broiler duodenal antimicrobial peptide 1(CATH1)and β-The expression of defensin 1(AVBD1)was significantly reduced(P＜0.05),and hypoxia inducible factor-1(HIF-1)α)Significant increase in expression(P＜0.05);The expression of CATH1 in the jejunum of broiler chickens in the 3%～9%FBL group was significantly reduced(P＜0.05),while HIF-1 was found in the jejunum of broiler chickens in the 6%and 9%FBL groups α Significant increase in expression(P＜0.05);The expression of CATH1 in the ileum of broiler chickens in the 6%and 9%FBL groups was significantly reduced(P＜0.05),while HIF-1 was found in the ileum of broiler chickens in the 9%FBL group α The expression was significantly increased(P＜0.05).The data from this experiment shows that 9%of FBL has a certain damaging effect on the intestines of broiler chickens,and it is believed that the amount of FBL added to the feed of broiler chickens should not exceed 6%.
万方数据
维普
