The aim of this study is to investigate the effects of fermented beer lees(FBL)on the growth performance,intestinal morphology,and expression of inflammatory factor genes in broiler chickens.1800 1-day-old white feathered broiler chickens were randomly divided into 4 groups,with 1 group consisting of 9 replicates and 1 replicate consisting of 50 chickens.Add 0%,3%,6%,and 9%FBL as experimental feed for a total of 42 days.FBL has a significant impact on the growth performance of broiler chickens.The addition of 9%FBL significantly reduced the average daily gain(ADG)of broiler chickens by 2.77%(P＜0.05),and the feed to meat ratio(F/G)significantly increased by 6.90%(P＜0.05).9%of FBL group broiler chickens showed a significant increase in duodenal crypt depth(P＜0.05)and a significant decrease in V/C value(P＜0.05);The ileal crypt depth of broiler chickens in the 6%and 9%FBL groups significantly increased(P＜0.05).6%and 9%FBL groups of broiler duodenal antimicrobial peptide 1(CATH1)and β-The expression of defensin 1(AVBD1)was significantly reduced(P＜0.05),and hypoxia inducible factor-1(HIF-1)α)Significant increase in expression(P＜0.05);The expression of CATH1 in the jejunum of broiler chickens in the 3%～9%FBL group was significantly reduced(P＜0.05),while HIF-1 was found in the jejunum of broiler chickens in the 6%and 9%FBL groups α Significant increase in expression(P＜0.05);The expression of CATH1 in the ileum of broiler chickens in the 6%and 9%FBL groups was significantly reduced(P＜0.05),while HIF-1 was found in the ileum of broiler chickens in the 9%FBL group α The expression was significantly increased(P＜0.05).The data from this experiment shows that 9%of FBL has a certain damaging effect on the intestines of broiler chickens,and it is believed that the amount of FBL added to the feed of broiler chickens should not exceed 6%.
维普
万方数据
