Screening for efficient and stable lactic acid bacteria bacteriocins against Escherichia coli.A strain of Lactobacillus plantarum isolated and identified from kimchi in Inner Mongolia Autonomous Region,named LT-1,the bacteriocin produced had the best bacteriostatic effect when the pH was 3,and the thermal stability was good,after 100℃ treatment,its bacteriostatic activity was slightly reduced,and the bacteriocin produced was more sensitive to papain,pepsin and proteinase K.The bacteriocin produced by LT-1 had good bacteriostatic activity against Escherichia coli ATCC25922 and clinical isolates of Escherichia coli.Whole genome sequencing of LT-1 predicted the bacteriocin-coding gene cluster,which mainly encodes lactococcin,enterococcin,and bacteriocin immunoproteins.The bacteriocins screened in this institute had good antibacterial activity,which laid a good foundation for the research and development of Escherichia coli anti-antibody products.
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