The effects of dietary supplementation of zinc methionine on growth performance,serum biochemical and antioxidant indicators in weaned piglets
Explore the effects of dietary addition of zinc methionine(ZM)on the growth performance,serum biochemistry,and antioxidant indicators of weaned piglets. 400 piglets of 28 day old Du Longchang ternary hybrid pigs were randomly divided into 4 groups,with 10 replicates in each group,with 10 piglets per replicate. Based on the zinc content,60 mg/kg of inorganic zinc was added to the control group feed,and 20,40,and 60 mg/kg of methionine zinc were used as substitutes for the inorganic zinc in the base diet for each experimental group feed. The experiment lasted for a total of 28 days. The experimental results showed that the average daily gain(ADG)of piglets in the 40 and 60 mg/kg ZM groups significantly increased by 10.95% and 12.51%,respectively(P<0.05),and the feed to meat ratio(F/G)significantly decreased by 9.72% and 10.02%,respectively(P<0.05);In addition,compared with the control group,the growth data of piglets in the 20 mg/kg ZM group showed a slight improvement,but the difference was not significant(P>0.05). The serum total protein(TP)and globulin(GLB)content of piglets in the ZM group with a concentration of 60 mg/kg were significantly increased(P<0.05);The serum immunoglobulin G(IgG)content of piglets in the 40 and 60 mg/kg ZM groups was significantly increased(P<0.05),the serum diamine oxidase(DAO)activity of piglets in the 60 mg/kg ZM group was significantly reduced(P<0.05),and the serum D-lactate(D-LA)content of piglets in the 40 and 60 mg/kg ZM groups was significantly reduced(P<0.05). ZM had an effect on serum urea nitrogen(UN),creatinine(Cr),and tumor necrosis factor in piglets-α(TNF)-α)The content had no significant effect(P>0.05). The total antioxidant capacity(T-AOC)of piglets in the ZM groups of 40 and 60 mg/kg was significantly increased(P<0.05);The total superoxide dismutase(T-SOD)activity in the serum of piglets in the 20~60 mg/kg ZM group was significantly increased(P<0.05),while the serum malondialdehyde(MDA)and hydrogen peroxide(H2O2)content in piglets in the 20~60 mg/kg ZM group were significantly reduced(P<0.05). The serum hydrogen peroxide(CAT)activity in piglets in the 20~60 mg/kg ZM group was significantly increased(P<0.05),and the serum glutathione peroxidase(GSH Px)activity in piglets in the 60 mg/kg ZM group was significantly increased(P<0.05). In summary,the optimal dosage of ZM for each indicator in this experiment is 60 mg/kg.