Research progress on mycoplasma synoviae and eggshell apex abnormality in chicken
Mycoplasma Synoviae(MS)is a pathogen that can cause infectious synovitis,respiratory diseases,and abnormal egg shell tips in poultry.Due to its ability to spread horizontally and vertically,MS is widely present worldwide and has caused significant economic losses to the global poultry industry.MS inactivated vaccines have high safety and protective efficiency,which can prevent MS from implanting in airbags and trachea.However,currently infected chicken flocks cannot be treated with live vaccines,and may even worsen the condition.Therefore,genetic engineering vaccines are considered the direction of MS vaccine research and development;The combination of antibiotics and vaccines has the best effect in immune prevention and control,but there are differences in antibiotic resistance among different countries and regions.In order to solve the problems in the prevention and treatment of MS,the development of new and efficient vaccines and antibiotic substitutes has also become a key research and development direction.Among them,Eggshell Apex Abnormality(EAA)is a popular and highly concerned abnormal egg phenomenon in recent years,which may be caused by MS infection.Therefore,this article introduces the etiology,clinical manifestations,epidemic status,treatment methods of MS,as well as the clinical manifestations and epidemic status of EAA caused by MS,and looks forward to the development trends of MS and EAA prevention and treatment.
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