In this experiment,flavonoids in fresh pomelo peel were extracted with ethanol after treating with high shear.Extraction yield of flavonoids were determined under different single factor conditions.The optimal extraction conditions for the extraction were:temperature was 70℃,extraction time was 1.5 h,concentration of ethanol was 80%,the ratio of liquid to material was 40 ∶ 1,times of high shear was 7 times,shear speed was 10 000 r/min,shear temperature was 50℃.Under optimal conditions,extraction yield of flavonoids was 0.880%.Compared to nonshear treating samples,the extraction yield increased by 13.6%,this result shows that high-speed shear treating is an effective way to improve the extraction yield of flavonoids.In addition,the extract has a strong antioxidant effect.