Optimization of Flavonoids from Ginkgo Biloba Using Respone Surface Analysis
This paper studies the technological conditions of extracting flavonoids from Ginkgo leaves. Extraction of flavonoids as an indicators, a single factor experiment and responsesurface method were used in ethanol extraction method. The extraction of flavonoids as an indicator, the use of ethanol reflux experiment, the single factor experiments and response surface analysis of the ethanol concentration, solid-liquid ratio, extraction time and ftxtraction temperature on the extraction of flavonoids. Analysing by Response Surface Method obtaines the optimum technological condition for Ginkgo leaves; ethanol concentration is 83%, the mass ratio is 1:22 g/mL, extracting time is 98 min and extracting temperature is 71 ℃. Under this condition the extraction of flavonoids is 18.38 mg/g. At the same time, the purified sample are characterized by IR spectra.
flavonoidsextractionanalysis of response surface methodcharacterization