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角鲨烯及其生物活性研究进展

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角鲨烯是由6个异戊二烯连接而成的不饱和三萜类化合物,是人体胆固醇代谢途径中一个关键的中间产物.本文系统论述了不同生物质中角鲨烯的含量及其活性研究进展.角鲨烯广泛存在于动、植物或微生物体内.在动物体内,尤以深海鲨鱼的肝脏中角鲨烯含量最为丰富.此外,在牦牛肉中角鲨烯的含量也较为丰富,这表明角鲨烯很可能与动物适应极端环境有关.在植物中角鲨烯的分布也很广,如橄榄油及其脱臭馏出物、苋菜籽油、米糠油、南瓜籽等均含有丰富的角鲨烯.角鲨烯有较广泛的生物活性,如携氧、调控胆固醇的代谢、抗氧化、抗肿瘤、解毒、抗辐射和抑制微生物生长等,被广泛应用于医药、化妆品和食品行业.
Research Process on Squalene and Bioactivities
Squalene is an unsaturated triterpene compound connected by six isoprene unites and also is a key intermediate of human cholesterol metabolism pathway.This paper systematically reviewed the contents of squalene in different biomasses and recent development in squalene's bioactivities.Squalene is existed widely in animals,plants and microorganisms.In animals,shark liver oil is considered the richest squalene source,and furthermore,yak meat is recendy also been found as a weel squalene source.These indicated that squalene is probably associated with animals adjusting themselves to adapt to the tough environment.Squalene is also widely distributed in plants,mainly including olive oil and its deodorizer distillate,amaranth grain oil,rice bran oil and pumpkin grain with amount of quantities.Squalene has been found possess various bioactivities,including carrying oxygen,regulating cholesterol metabolism,antioxidation,anticancer,detoxifier,anti-radiation and inhibiting microbial growth etc.and is widely applied in cosmetics,pharmaceutical and food industry.

squalenebiomasscontentbioactivitiesapplication

刘纯友、马美湖、靳国锋、耿放、王庆玲、孙术国

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华中农业大学食品科技学院 武汉430070

中南林业科技大学食品科学与工程学院 长沙410004

角鲨烯 生物质 含量 生物活性 应用

2015

中国食品学报
中国食品科学技术学会

中国食品学报

CSTPCDCSCD北大核心EI
影响因子:1.079
ISSN:1009-7848
年,卷(期):2015.15(5)
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