Exosomes are nanoscale(40-160 nm in diameter)extracellular vesicles that play a role in cell signal trans-duction,immune response and antigen presentation.They can be isolated from various body fluids,including serum,saliva,urine,cerebrospinal fluid and emulsion,etc.Milk-derived exosomes are endogenous delivery vehicles which con-tain a variety of functional molecules such as proteins and miRNA,many of which are related to human immune func-tion.Milk-derived exosomes can be absorbed by human intestine and exert healthy effects through ingestion of milk.This article summarizes domestic and foreign reports on the relationship between milk-derived exosomes and microorganisms,as well as the research results of our team.In this article,the biogenesis process and main components of exosomes,the relationship between exosomes and pathogenic microbial infection,and the effects of milk-derived exosomes on in-testinal microorganisms were expounded.It provides a reference for studying the nutritional and health effects of milk-de-rived exosomes on human body.
关键词
外泌体/微生物/肠道菌群/牛乳/母乳
Key words
exosomes/microorganisms/gut microbiota/bovine milk/human breast milk
维普
万方数据