中国食品学报2024,Vol.24Issue(4) :420-430.DOI:10.16429/j.1009-7848.2024.04.040

食品蛋白增维结构精密构筑研究进展

Research Progress on the Precise Construction of Hierarchical Structures of Food Proteins

李煦源 陈正行 王涛
中国食品学报2024,Vol.24Issue(4) :420-430.DOI:10.16429/j.1009-7848.2024.04.040

食品蛋白增维结构精密构筑研究进展

Research Progress on the Precise Construction of Hierarchical Structures of Food Proteins

李煦源 1陈正行 1王涛1
扫码查看

作者信息

  • 1. 江南大学 粮食发酵与食品生物制造国家工程研究中心 江苏无锡 214122
  • 折叠

摘要

增维结构为短程有序性单元结构在多维空间限域堆积,进而形成长程可控性高级结构,其特征为各单元结构定向排布且在尺度、维度上均具高度可编程性.鉴于动态化设计逻辑及标准化构筑机制,这种基于类似单元结构所形成的空间多样化高级组织架构,在功能食品的开发中具有重要应用.目前,增维结构的设计开发大多基于人工高分子或工程化蛋白,而在天然蛋白结构中鲜有报道,缺乏对蛋白折叠的过程控制是其首要原因.本文基于蛋白质共架技术,从介观重构、纳米雕刻及增维定制3个方面综述食品蛋白增维结构精密构筑研究进展.探讨构建食品蛋白高值化利用关键技术体系的思路和方法,以期为我国食品蛋白产业的发展提供理论和实践支持.

Abstract

Hierarchical structures are long-range controllable high-level structures that are assembled by confined assem-bly at the multidimensional spaces of unit structures with short-range orders.Hierarchical structures are characteristic of directional arrangement by unit structures and high programmability in their scales and dimensions.Due to dynamic de-sign logic and normalized construction mechanism,such highly organized and spatially diverse structures assembly with similar unit structures may find critical applications in design of functional foods.However,current design and develop-ment of hierarchical structures are based on artificial polymers and engineered proteins,while it is yet to have studies focused on natural proteins.The primary reason is the lack of process control of protein folding.In this paper,the re-search progress on the precise construction of hierarchical structures of food proteins is reviewed,which is based on pro-tein co-construction technology from three aspects:mesoscopic reconfiguration,nanoscale carving,and hierarchical cus-tomization.This work provides new ideas and methods for constructing the key technological system for value-added uti-lization of food proteins,trying to provide certain theoretical and practical support for promoting the development of food protein industry in China.

关键词

增维结构/限域堆积/蛋白改性/精密构筑

Key words

hierarchical structures/confined assembly/protein modification/precise construction

引用本文复制引用

基金项目

国家自然科学基金(32172138)

江苏省优秀青年基金(BK20220154)

出版年

2024
中国食品学报
中国食品科学技术学会

中国食品学报

CSTPCDCSCD北大核心EI
影响因子:1.079
ISSN:1009-7848
参考文献量50
段落导航相关论文