Hierarchical structures are long-range controllable high-level structures that are assembled by confined assem-bly at the multidimensional spaces of unit structures with short-range orders.Hierarchical structures are characteristic of directional arrangement by unit structures and high programmability in their scales and dimensions.Due to dynamic de-sign logic and normalized construction mechanism,such highly organized and spatially diverse structures assembly with similar unit structures may find critical applications in design of functional foods.However,current design and develop-ment of hierarchical structures are based on artificial polymers and engineered proteins,while it is yet to have studies focused on natural proteins.The primary reason is the lack of process control of protein folding.In this paper,the re-search progress on the precise construction of hierarchical structures of food proteins is reviewed,which is based on pro-tein co-construction technology from three aspects:mesoscopic reconfiguration,nanoscale carving,and hierarchical cus-tomization.This work provides new ideas and methods for constructing the key technological system for value-added uti-lization of food proteins,trying to provide certain theoretical and practical support for promoting the development of food protein industry in China.
hierarchical structuresconfined assemblyprotein modificationprecise construction
维普
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