中国食品学报2024,Vol.24Issue(5) :103-125.DOI:10.16429/j.1009-7848.2024.05.008

细胞培养肉高效合成的生物学基础与技术挑战

Biological Basis for Efficient Synthesis of Cultured Meat and Technical Challenges

关欣 周景文 王守伟 李春保 陈坚
中国食品学报2024,Vol.24Issue(5) :103-125.DOI:10.16429/j.1009-7848.2024.05.008

细胞培养肉高效合成的生物学基础与技术挑战

Biological Basis for Efficient Synthesis of Cultured Meat and Technical Challenges

关欣 1周景文 1王守伟 2李春保 3陈坚1
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作者信息

  • 1. 江南大学 未来食品科学中心 江苏无锡 214122
  • 2. 中国肉类食品综合研究中心 北京 100068
  • 3. 南京农业大学食品科技学院 南京 210095
  • 折叠

摘要

随着社会发展水平的不断提升,全球肉制品消耗量快速增长.细胞培养肉是农业食品科技的一场革命,随着国际上细胞培养肉工程化技术的迅速发展,国内在这方面的差距逐步显现.本文综述细胞培养肉高效合成的生物学基础,包括动物细胞功能维持与发育过程机制,关键生长因子解析与生物合成,细胞大规模低成本培养关键技术以及细胞培养肉食用品质提升的生物学过程,讨论细胞培养肉工业化制造面临的技术挑战,并对细胞培养肉技术的未来重点攻关方向进行展望,为实现细胞培养肉的可持续生物制造提供理论和实践依据.

Abstract

With the increasing level of social development,the global consumption of meat products is growing rapidly.Cultured meat is a revolution in agri-food science and technology.With the rapid development of cultured meat engineer-ing technology in the international arena,the gap in this regard in China has gradually emerged.This work reviewed the biological basis for efficient synthesis of cultured meat,including the mechanism of functional maintenance and develop-mental process of animal cells,the summary of animal cell growth factors and their synthesis strategies,the key tech-nologies of the large-scale and low-cost culture of animal cells,and the biological process for improving the edible quality of cultured meat.Furthermore,this study discussed the technological challenges for industrialized manufacturing of cultured meat,and then provided a perspective on the future focus of cultured meat technology,so as to provide a the-oretical and practical basis for achieving sustainable biomanufacturing of cultured meat.

关键词

细胞培养肉/食品合成生物学/工程化/低成本/大规模

Key words

cultured meat/food synthetic biology/engineering/low cost/large scale

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基金项目

中国工程院咨询项目(2023-XZ-79)

出版年

2024
中国食品学报
中国食品科学技术学会

中国食品学报

CSTPCDCSCD北大核心EI
影响因子:1.079
ISSN:1009-7848
参考文献量33
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