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食源性抗氧化肽的构效关系及强化方法

Structure-activity Relationship and Strengthening Methods of Food-derived Antioxidant Peptides

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食源性多肽因具有较高的营养价值和多种生物活性,备受研究者关注.然而,由于天然食源性多肽的来源和提取工艺受限,其抗氧化性能在实际应用中逐渐无法满足抗衰老和慢性疾病防治的需求.本文综述了食源性抗氧化多肽的来源,分析了多肽抗氧化性能与水解度、氨基酸组成及序列、分子质量及二级结构之间的构效关系,并探讨了当前多肽抗氧化性强化方法的研究现状及存在的问题.这些工作将为食源性抗氧化肽的应用和拓展提供重要支持.
Food-derived peptides have attracted considerable attention from researchers due to their high nutritional value and diverse bioactivities.However,limitations in the natural sources and extraction processes of food-derived peptides have led to their antioxidant capabilities gradually falling short of meeting the demands for anti-aging and the prevention of chronic diseases in practical applications.This paper reviewed the sources of food-derived antioxidant peptides,ana-lyzed the structure-activity relationships between peptide antioxidant properties and factors such as hydrolysis,amino acid composition and sequence,molecular weight,and secondary structure.Additionally,the curr-ent research status and exist-ing issues of methods to enhance the antioxidant properties of peptides were discussed.These efforts will provide crucial support for the application and expansion of food-derived antioxidant peptides.

food-derived peptidesstructure-activity relationshipstrengthening methodantioxidant activity

康记珍、许承志、王希搏、汪海波

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武汉轻工大学食品科学与工程学院 武汉 430040

武汉轻工大学化学与环境工程学院 武汉 430040

湖北瑞邦生物科技有限公司 湖北荆州 434008

食源性多肽 构效关系 强化方法 抗氧化性

国家自然科学基金

22178277

2024

中国食品学报
中国食品科学技术学会

中国食品学报

CSTPCD北大核心EI
影响因子:1.079
ISSN:1009-7848
年,卷(期):2024.24(5)
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