摘要
豌豆蛋白是一种安全性高,健康营养,价格低廉的植物蛋白.近年来,越来越多具有生物活性的豌豆肽被挖掘出来,豌豆生物活性肽的开发既可以高值化利用植物蛋白,又对维护人类健康起到积极作用.本文以豌豆肽为对象,重点围绕豌豆肽发挥活性的体内外效果、相关调节方式以及关键信号通路等方面,概述豌豆肽生物活性与作用机制的研究进展,具体包括抗氧化、辅助降血压、辅助降血糖、抗菌、免疫调节、抗肿瘤、调节肠道菌群和促进益生菌生长等活性,并展望豌豆肽未来的研究方向,以期为豌豆生物活性肽的深入研究与综合利用提供参考.
Abstract
Pea protein,a plant-based protein sourced from Pisum sativum,is distinguished by its high safety,nutritional efficacy,and cost advantages.This protein type has been the subject of growing interest due to its favorable nutritional profile and affordability,making it a viable alternative for a broad consumer base,including those following vegetarian or vegan dietary practices.In recent years,the field of bioactive peptide research has witnessed a surge in the exploration of peptides with biological activities derived from pea protein.The development and investigation of these peptides are of significant importance,as they not only represent a high-value application of plant proteins but also contribute positively to human health maintenance.This review delves into the bioactivity and mechanism of action of pea peptides,with a specific focus on the effects observed both in vivo and ex vivo,as well as the associated regulatory mechanisms and key signaling pathways.The documented bioactivities of pea peptides include,but are not limited to,antioxidant capabilities,auxiliary blood pressure reduction,glycemic control,antimicrobial properties,immunomodulatory effects,anti-tumor po-tential,intestinal flora regulation,and the promotion of probiotic growth.Furthermore,this review anticipates and propos-es future research directions for pea peptides,aiming to offer a framework that guides the deeper investigation and holis-tic application of these bioactive peptides in nutritional science and public health.
基金项目
湖南省自然科学基金面上项目(2022JJ30587)
泰山产业领军人才项目(LJNY202004)