Recent Advances on the Preparation,Cell Functions and Absorption of Hyaluronic Acid and Its Regulatory Effect on Intestinal Homeostasis and Inflammation
Hyaluronic acid(HA)is a non-sulfated glycosaminoglycan.After HA was approved to become a'new food ingredient'in 2021,it provoked the widespread interest from both food researchers and industrial field.However,in re-cent years,more and more research has shown that the biological activity of HA can haveeffecton pro-inflammatory or anti-inflammatory aswellas pro-proliferation or anti-proliferation according to its different molecular weight.Therefore,in order to efficiently and accurately improve the application value of HA in food health industry,it is necessary to com-prehensively conclude and summarize the study progress of HA in food science and technology,according to its differ-ences in molecular weight.In views of this idea,this paper,based on the overview of developing progress of HA appli-cation,focuses on preparation,cell activity and absorptionof HA with different molecular weights.And it describes the modulatory effect of HA towards intestinal tract from two dimensions,which are homeostasis maintenance and inflamma-tion regulation,aiming to fully explore the potential of HA in the field of nutrition and health industry.
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