首页|母乳低聚糖对婴儿肠道菌群及认知功能的影响

母乳低聚糖对婴儿肠道菌群及认知功能的影响

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母乳低聚糖(HMOs)是母乳中具有独特结构的复杂糖类物质,其多样性远高于其它哺乳动物乳.HMOs的功能作用可从婴儿肠道菌群的初步建立一直持续到成年阶段,包括支持有益细菌生长和抗病原菌黏附等,其也具有在认知方面产生有益效果的潜力.关于HMOs是否能够通过调节肠道菌群并借助肠-脑轴来促进婴儿大脑的健康发育,值得进一步研究.本文综述HMOs的组成、结构,重点阐述HMOs在塑造婴儿肠道菌群中的作用,并探讨两者及其产生的代谢物通过肠-脑轴对婴儿认知的促进作用,旨在为推进HMOs在婴儿配方食品中的应用提供理论参考.
Effects of Human Milk Oligosaccharides on Intestinal Flora and Cognitive Function of Infants
Human milk oligosaccharides(HMOs)are complex carbohydrates with unique structures in human milk,and their diversity is much higher than that of other mammalian milk.The functional role of HMOs can continue from the initial establishment of infant gut microbiota to adulthood,including supporting beneficial bacterial growth and anti-pathogen adhesion.It also has the potential to produce beneficial effects in cognition.It is worth further studying whether HMOs can promote the healthy development of the infant brain by regulating the intestinal flora and using the gut-brain axis.This paper reviewed the composition and structure of HMOs,focused on the role of HMOs in shaping the intestinal flora of infants,and discussed the promotion of HMOs and their metabolites on infant cognition through the gut-brain ax-is,aiming to provide a theoretical reference for promoting the application of HMOs in infant formula.

human milk oligosaccharidesintestinal florabrain development

马美红、乌日娜、刘语萌、丁瑞雪、武俊瑞

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沈阳农业大学食品学院 沈阳 110866

辽宁省食品发酵技术工程研究中心 沈阳 110866

沈阳市微生物发酵技术创新重点实验室 沈阳 110866

母乳低聚糖 肠道菌群 大脑发育

2024

中国食品学报
中国食品科学技术学会

中国食品学报

CSTPCD北大核心EI
影响因子:1.079
ISSN:1009-7848
年,卷(期):2024.24(8)