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联合疫苗研发现状及趋势

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作为经济有效的卫生干预手段之一,疫苗预防接种在控制和消灭传染性疾病方面发挥着至关重要的作用.根据免疫程序,及时完成接种可以确保机体产生有效的免疫反应.相较于单一疫苗,集多种抗原为一体的联合疫苗减少了因多针次接种而造成的不便,提升了接种覆盖率,筑牢了免疫防线,为保障公众卫生发挥了积极作用.随着相关学科和制备技术的不断发展,越来越多的疫苗产品组合问世,在世界各国及地区的免疫规划中发挥着至关重要的支撑作用.本文从联合疫苗研发历史及其优势、研发现状和趋势以及面临的挑战等方面进行概述,以期为我国联合疫苗的研发提供相应参考.
Development Status and Trends of Combined Vaccines
As a cost-effective health intervention,vaccination plays a vital role in controlling and eradicating infectious diseases.Following the immunization schedule and performing vaccination in a timely manner can ensure that the body generates an effective immune response.Compared with stand-alone vaccines,combined vaccines integrate multiple antigens,reduce the inconveniences caused by multiple injections,improve vaccination coverage,consolidate the immune barrier,and contribute positively to public health.With the continuous development of relevant disciplines and vaccine preparation technologies,an increasing number of combined vaccine products are being introduced,serving as essential components in immunization programs worldwide.This article summarizes the history and advantages of combined vaccines,the current status and trends in research and development,and the challenges faced,aiming to provide a reference for the development of combined vaccines in China.

combined vaccinesstand-alone vaccinesimmunizationcoverageresearch and development

刘一凡、杨盛然、王佑春

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中国医学科学院医学生物学研究所

联合疫苗 单一疫苗 免疫接种 覆盖率 研发

2024

中国食品药品监管
中国医药报社

中国食品药品监管

影响因子:0.099
ISSN:1673-5390
年,卷(期):2024.(11)