Analysis of the Demand and Suggestions for Pediatric Medication Development in China Based on the Market Status of Essential Drugs for Children
China faces a significant demand for pediatric medications.However,the challenges of developing children's drugs-such as the difficulty of conducting clinical trials,high R&D costs,and technical complexities-have led to a long-standing shortage of children's drugs.This study analyzes the market availability of children's medicines in China based on the eighth edition of the World Health Organization's(WHO)Model List of Essential Medicines for Children and the list of pediatric drugs encouraged for development by the National Medical Products Administration(NMPA).The analysis focuses on shortages in pediatric-specific drugs,shared adult-pediatric medications,and empirically used drugs.Based on pediatric clinical needs and current market conditions,priority areas identified include:development of inhaled formulations for respiratory conditions,optimization of dosing for immunomodulators,anti-cancer drugs,ophthalmic and dermatological medications;and development of new products and formulations for rare disease,cardiovascular diseases,and endocrine disorders.Additionally,strategies such as expediting the introduction of foreign pediatric drugs into the domestic market,developing new oral liquid formulations,downsizing adult injectable doses for pediatric use,and establishing supportive policies could effectively mitigate pediatric drug shortages.
万方数据
维普
