Study on Antimicrobial Activity of Chitosan Against Staphylococcus aureus
The antibacterial activity of chitosan against Staphylococcus aureus was studied and the effect of different chitosan concentrations, pH values, metal ions, the acetic concentrations on the antimicrobial activity of chitosan were investigated. The optimal conditions were determinated by orthogonal test. Results showed that the inhibition of chitosan on Staphylococcus aureus increased with the chitosan concentration, the antibacterial activity of chitosan was the best when it was dissolved in 2% acetic, the pH value of culture medium was 6.0, and the influence of chitosan concentration, pH value of culture medium and acetic concentration on the antibacterial activity were chitosan concentration,pH value,acetic concentration as follows. Antibacterial activity of chitosan decreased when metal ions existed.