Effect of Early Nutritional Intervention on Nutritional Status and Incidence of Sepsis in Low/Very Low Birth Weight Infants
[Objective]To investigate the effects of early nutritional intervention on the nutritional status,physical development and incidence of sepsis in low/very low weight infants.[Method]Totally 200 cases of low/very low weight infants admitted to our hospital from August 2020 to August 2022 were selected for the study,and were divided into 100 cases in the observation group and 100 cases in the control group according to the random number method.The differences in gestational age,sex,birth weight,body length and head circumference between the two groups were not statistically significant(P＞0.05).In the control group,conventional nutritional interven-tion was used for low/very low weight children,and in the observation group,a combination of early enteral and parenteral nutritional intervention was used.The changes in serum nutritional indicators and infection indicators,as well as physical development and the occur-rence of late-onset sepsis in the two groups of low/very low weight infants before and after intervention were compared.[Result]Compared with conventional nutritional intervention,early nutritional intervention significantly increased serum ALB,and BUN levels in low/very low weight children(all P＜0.05),but had no specific advantage on weight and length growth(P＞0.05).In addition,the incidence of late-onset sepsis was 12％in the control group and 3％in the observation group,and the incidence of late-onset sepsis in the observation group was significantly lower than that in the control group(x2=5.838,P＜0.05),and the serum WBC,CRP and PCT levels in the observation group were significantly lower than those in the pre-intervention and control groups after the nutritional intervention(P＜0.05).[Conclu-sion]Early nutritional intervention can improve the nutritional status of children,ensure physical development,and reduce the incidence of late-stage sepsis.Clinically,active early nutritional intervention should be performed for low/very low weight children who can tolerate early nutritional intervention.
万方数据
维普
