Effect of Early Enteral Nutrition Therapy on Nutritional Status and Physical Development of Preterm Infants
[Objective]To investigate the effects of early enteral nutrition therapy on the nutritional status and physical development of preterm infants,as well as the occurrence of complications.[Method]Totally 100 cases of preterm infants who were delivered and born in Wuhu Second People's Hospital from January 2020 to October 2023 and received inpatient delivery and treatment were selected as the study subjects,and the 100 cases of preterm infants were divided into the observation group(given enteral nutrition treatment within 24 hours after birth)and the control group(given enteral nutrition treatment after 24 hours of birth)according to the random number table.In the early enteral nutrition treatment group,enteral nutrition treatment was given within 24 hours after birth,and the preterm infants in the control group were given enteral nutrition after 24 hours of birth,and the amount,mode,and rate of increase of enteral nutrition feeding were consistent with that of the observation group.We compared the serum nutritional indexes of preterm infants in the two groups at the time of admission and at 7 days of age,including albumin(ALB),prealbumin(PA),haemoglobin(HGB)and transferrin(TRF);we compared the physical development indexes of preterm infants at the time of admission,at 7 days of age and at 14 days of age,including body length,body mass index(BMI)and head circumference;as well as the complications such as feeding intolerance,cholestasis,necrotizing small intestinal colitis,sepsis and other complications Occurrence.[Result]Serum ALB,PA,HGB and TRF levels of preterm infants in the early enteral nutrition group were significantly higher than those of preterm infants in the control group at 7 days of age(P＜0.05).On physical development indicators,there was no difference in BMI,length and head circumference between the two groups of preterm infants at the time of admission and at the age of 7 days(P＞0.05),and at the age of 14 days,there was still no difference in length and head circumference between the two groups of preterm infants,whereas the preterm infants in the early enteral nutrition treatment group had a higher BMI than that of the control group(P=0.012).The complication rate of preterm infants in the early enteral nutrition treatment group was 18％,compared with 36％in the control group,with a statistically significant difference(P=0.043).[Conclusion]Early enteral nutrition therapy for preterm infants can improve their nutritional status,promote growth and development,and the total incidence of complications did not increase.Therefore,we should provide enteral nutrition therapy for preterm infants as early as possible on the basis of the routine treatment of preterm infants.
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