A Qualitative Evidence-Based Study on Glycolipid Metabolism Effects of Bird's Nest and Sialic Acid
[Objective]This research is a systematic review about the health effects of exogenous supplementation of bird's nest and sialic acid on glycolipid metabolism.[Method]The literature search was restricted to studies published in English and Chinese language for the period of January 2012 until February 2023 using"bird's nest","sialic acid","glucose metabolism"and"lipid metabolism"as keywords.Eight references meeting the exclusion criteria were included in this review,including five references about the effect of sialic acid on glycolipid metabolism and three references about the effect of bird's nest on glycolipid metabolism,all of which were randomized controlled animal studies.[Result]Five studies on sialic acid and three studies on bird's nest showed that supplementation with bird's nest or sialic acid reduced serum cholesterol levels,atherosclerotic plaque area,HOMA-IR values and area under the OGTT curve in experimental animals on a high-fat diet(P-values were all less than 0.05),which could benefit glycolipid metabolism in animals.However,the level of evidence was poor and no human studies with high evidence validity were included.[Conclusion]Bird's nest and sialic acid are beneficial in improving glycolipid metabolism in experimental animals,but it is not clear whether they have a same regulatory effect on human bodies and further studies are needed to verify it.
万方数据
维普
