首页|维生素D对儿童特异性皮炎的影响分析

维生素D对儿童特异性皮炎的影响分析

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目的:探讨维生素D对儿童特异性皮炎的影响。方法:前瞻性选取2021年1月—2023年12月在本院收治的儿童特异性皮炎30例作为研究对象纳入观察组,同时期选取本院体检的健康体检者45名作为对照组,比较两组维生素D水平及分布情况,观察组进一步根据疾病严重程度分为轻度组、中度组、重度组,以及患儿治疗前后维生素D水平。结果:观察组血清维生素D水平低于对照组(P<0。05),观察组血清维生素D水平不足和缺乏占比均更高于对照组(P<0。05);3组SCOR特异性皮炎评分比较差异有统计学意义(P<0。05),缺乏组患者SCOR特异性皮炎评分明显高于其他2组(P<0。05),且不足组SCOR特异性皮炎评分又高于正常组(P<0。05);3组维生素D水平比较差异有统计学意义(P<0。05),重度组患者维生素D水平低于其他2组(P<0。05),且不足组维生素D水平又低于轻度组(P<0。05);观察组患儿治疗后维生素D、SCOR特异性皮炎评分均高于治疗前(P<0。05)。结论:维生素D水平不足和缺乏与儿童特异性皮炎的发生有关,维生素D的补充可以改善患儿的疾病严重程度。
Effect of Vitamin D on Specific Dermatitis in Children
[Objective]To investigate the effect of vitamin D on specific dermatitis in children.[Method]Totally 30 cases of specific dermatitis in children AD mitted to our hospital from January 2021 to December 2023 were prospectively selected as study subjects to be included in the observation group,and 45 healthy physical examination subjects from our hospital during the same period were selected as control group.Vitamin D levels and distribution of the two groups were compared,and the observation group was further divided into mild group,moderate group and severe group according to the severity of the disease,and vitamin D levels before and after treatment.[Result]The serum vitamin D level in the observation group was lower than that in the control group(P<0.05),and the proportion of vitamin D deficiency and deficiency in the observation group was higher than that in the control group(P<0.05).The score of SCOR specific dermatitis was significantly different among the three groups(P<0.05).The score of SCOR specific dermatitis in the deficiency group was significantly higher than that in the other two groups(P<0.05),and the score of SCOR specific dermatitis in the deficiency group was higher than that in the normal group(P<0.05).There was statistical significance in vitamin D level among the three groups(P<0.05).The level of vitamin D in the severe group was lower than that in the other two groups(P<0.05),and the level of vitamin D in the insuf-ficient group was lower than that in the mild group(P<0.05).The scores of vitamin D and SCOR specific dermatitis in observation group were higher after treatment than before treatment(P<0.05).[Conclusion]Insufficient and deficient vitamin D levels are associated with the occurrence of child specific dermatitis,and vitamin D supplementation can improve the severity of the disease in children.

specific dermatitisvitamin Dchildren

程佳伟、施健、花志祥、李隽

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南通大学第二附属医院/南通市第一人民医院,江苏南通 226000

特异性皮炎 维生素D 儿童

江苏省中医药局项目

MS2022091

2024

中国食物与营养
中国农业科学院 国家食物与营养咨询委员会

中国食物与营养

CSTPCD
影响因子:0.754
ISSN:1006-9577
年,卷(期):2024.30(4)
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