Qualitative Evidence-Based Study on Effect of Bird's Nest and Sialic Acid on Immune Function
[Objective]To systematically evaluate the effect of bird's nest and sialic acid on immune function.[Method]Relevant studies published from January 2012 to June 2023 on PubMed,Embase,China National Knowledge Infrastructure(CNKI),Wanfang Database,and China Biology Medicine disc(CBMdisc)were searched and selected based on the inclusion and exclusion criteria.The SYRCLE's risk of bias tool for animal studies was used to assess the bias of the selected studies.[Result]A total of 11 studies were included,including 7 animal studies,4 vitro experiments.Despite different sources,routes of administration,intervention duration or intervention doses of bird's nest and sialic acid were used in these studies.The results of this systematic review showed that bird's nest and sialic acid had the function of enchaning immune and antivirus of animals,which showed a dose dependent effect.[Conclusion]Bird's nest and sialic acid have the effect of enhancing immune and antivirus to animals.
edible bird's nestsialic acidimmuneantiviralevidence-based study